To date, in utero exposure to tamoxifen has not been shown to cause vaginal adenosis, or clear-cell adenocarcinoma of the vagina or cervix, in young women. The biological activity of N-desmethyl tamoxifen appears to be similar to that of tamoxifen. If age at the time of diagnosis is considered, there were cases of endometrial cancer among participants 49 randomized to NOLVADEX compared to among participants randomized to placebo RR. These elevations were not accompanied by clinical hyperthyroidism. Do not take Nolvadex to lower your chance of getting breast cancer if You ever had blood clot that needed medical treatment. In these nolvadex acquista on line trials, an increased number of cases of deep vein thrombosis, pulmonary embolus, stroke, and endometrial cancer were observed on the tamoxifen arm compared to the placebo arm.